As seen in
In Control, Wherever You Are.
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FODZYME® Home Kit
Your everyday essential. A jar built for the kitchen counter.
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FODZYME® On-The-Go Kit
Our most powerful dose yet. 33% more enzyme activity — ideal for dining out or travel.
Some Foods Can Leave Us Feeling Bloated, Gassy, Constipated, Or Even Anxious
Wheat Bread
Wheat bread can be high in fructans, and medium in GOS FODMAPs. To enjoy, simply add a full dose of FODZYME® on the first bite and chew.
Garlic
Garlic can be high in fructans. To enjoy, simply sprinkle FODZYME® directly on the meal and mix.
Wheat Pasta
Wheat pasta can be high in fructans, and medium in GOS FODMAPs. To enjoy, simply add a full dose of FODZYME® on the first bite and chew.
Onion
Onion can be high in fructans, and medium in GOS FODMAPs. To enjoy, simply sprinkle FODZYME® directly on the meal and mix.
Beans
Beans can be high in fructans, and high in GOS FODMAPs. To enjoy, simply sprinkle FODZYME® directly on the meal and mix.
Cheese
Cheese can be high in lactose. To enjoy, simply sprinkle FODZYME® directly on the meal and mix.
Many healthy foods, such as garlic, onions, wheat, beans, and dairy, can cause digestive trouble for some individuals.
These foods contain FODMAPs—natural carbohydrates that can ferment rapidly in the gut and lead to symptoms, particularly for those with sensitive digestion or IBS.
While FODMAPs are not bad—they’re actually prebiotics—they can trigger discomfort in some individuals.
Restricting Healthy High-FODMAP Foods Isn't Intended To Be A Long-Term Solution…
The standard approach has been to eliminate high-FODMAP foods, which can be restrictive, confusing, and difficult to maintain.
Avoidance means missing out on favorite meals and social occasions.
We’re changing that with novel, patent-pending enzymes.
Why People Love FODZYME®
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"It took a few but Fodzyme was able to restore my gut’s balance so that I don’t need Miralax to have regularity."
CHARI -
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"FODZYME makes my life more normal again. I don’t avoid and/or dread eating out anymore. I can travel with less stress."
BROOKE H. -
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"It has changed my life! I can eat foods I have eaten in years! It really works!"
DENISE H. -
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"So helpful to take the stress out. Now I don't bloat and I don't have discomfort after eating. And meals are blissfully not stressful!"
MADELINE H.
Why People Love FODZYME®
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⭐⭐⭐⭐⭐
"It took a few but Fodzyme was able to restore my gut’s balance so that I don’t need Miralax to have regularity."
CHARI -
⭐⭐⭐⭐⭐
"FODZYME makes my life more normal again. I don’t avoid and/or dread eating out anymore. I can travel with less stress."
BROOKE H. -
⭐⭐⭐⭐⭐
"It has changed my life! I can eat foods I have eaten in years! It really works!"
DENISE H. -
⭐⭐⭐⭐⭐
"So helpful to take the stress out. Now I don't bloat and I don't have discomfort after eating. And meals are blissfully not stressful!"
MADELINE H.
Tasteless Formulation
FODZYME® is formulated as a tasteless powder to ensure maximum contact between its digestive enzymes and FODMAP-containing foods, allowing for more effective breakdown of FODMAPs during digestion. Unlike capsules, the powder mixes directly with food, optimizing enzyme performance and supporting better digestive relief.
Our formulation consists of clinically and scientifically studied microbial enzymes characterized at both academic institutions, and research partners.
ACTIVE INGREDIENTS:
ENZYME BLEND (32MG PER G)
Our fructan hydrolase is the first ever enzyme to target fructans like inulin, fructo-oligosaccharides (FOS), and levan.
Our alpha-galactosidase enzyme can effectively break down the galacto-oligosaccharides (GOS) or galactans (“O” in FODMAPs).
Our lactase enzyme (also called β-D-galactosidase) can break down lactose (the “D” in FODMAPs).
Other ingredients: dextrin (from non-GMO corn)
Contains no GMOs, gluten, milk, egg, casein, soy, or artificial colors or flavors.
Soy-free
Egg-free
Non-GMO
Soy-free
Egg-free
Non-GMO
Soy-free
Egg-free
Non-GMO
Soy-free
How It Works
Evidence & Research
Simulator of the Human Intestinal Microbial Ecosystem (SHIME®)
FODZYME® is supported by two peer-reviewed publications in Gastro Hep Advances. In a SHIME® study (Castro Ochoa et al., 2023), it degraded 90% of fructans within 30 minutes while preserving short-chain fatty acid (SCFA) and butyrate production — unlike a strict low-FODMAP diet, which depletes SCFAs critical for colonic microbiome health. In an IRB-approved clinical cohort study independently analyzed at SUNY Downstate (Kaye et al., 2026), 78% of participants reported improvement in bloating and flatulence from FODMAP ingestion after 4 weeks, with significant improvements in quality of life and mental well-being (all P<.01).
Feel The Difference With Your First Meal
Mix directly or apply evenly on meals.
Double dosage when feasting. Chew well. Enjoy.
And many more delicious and nutritious foods
And many more delicious and nutritious foods
Not a Probiotic. Not a Pill.
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| FODMAP Enzyme Formula | ||
| Powder Formula For Better Mixing | ||
| Scientifically Proven Formula | ||
| Third-Party Tested | ||
| Certified low-FODMAP |
Our Scientific Advisory Board Includes Experts In Gastroenterology, Biotechnology, Computational Biology, And Nutrition, Representing World-Class Institutions.
Our Scientific Advisory Board Includes Experts In Gastroenterology, Biotechnology, Computational Biology, And Nutrition, Representing World-Class Institutions.
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William D. Chey, MD
Advisor, Professor of Gastroenterology at the University of Michigan and Board member at the American College of Gastroenterology (ACG) and Rome Foundation
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Shalaka Samant, PhD
Founding Scientist at Kiwi Biosciences, former postdoctoral researcher at the Yale University School of Medicine
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Thomas Wallach, MD
Advisor, Assistant Professor at SUNY Downstate Medical Center, Pediatric Gastroenterology
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Jocelyn Wells, MS, RDN
A dietitian with a Master's in Clinical Nutrition, Jocelyn leads FODZYME®'s healthcare partnerships. She bridges the latest research in digestive health and nutrition guidelines to help clinicians bring digestive relief to patients navigating IBS and FODMAPs.
FAQs & Answers
How quickly does FODZYME® work? When will I feel something?
How quickly does FODZYME® work? When will I feel something?
FODZYME® begins breaking down FODMAPs immediately upon contact with food. In a peer-reviewed study (Castro Ochoa et al., Gastro Hep Advances, 2023), it degraded up to 90% of fructans within 30 minutes under simulated gastric conditions. This rapid action breaks down FODMAPs in the stomach and upper small intestine — before they reach the colon where bacterial fermentation causes bloating and gas.
Most users notice the absence of their usual symptoms 4–8 hours after a FODMAP-rich meal, consistent with normal gastrointestinal transit time. In an IRB-approved clinical study (Kaye et al., Gastro Hep Advances, 2026), 78% of participants reported improvement in bloating and flatulence from FODMAP ingestion after 4 weeks (P<.01).
Can I use FODZYME® every day?
Can I use FODZYME® every day?
Yes, FODZYME®is designed for safe daily use. Its enzymes are naturally occurring and work specifically on FODMAPs without interfering with normal digestion or nutrient absorption. Regular use can help manage symptoms and expand dietary choices for those following a low FODMAP diet.
Will FODZYME® interfere with my medications?
Will FODZYME® interfere with my medications?
FODZYME® is generally considered safe to use alongside most medications, as its enzymes work specifically on FODMAPs in the digestive tract. However, it’s always a good idea to consult your healthcare provider or pharmacist before starting any new supplement—especially if you’re taking prescription medications.
Individual responses can vary. If you notice any unusual symptoms or changes in medication effectiveness, discontinue use and consult your healthcare provider immediately.
Is FODZYME® a cure for conditions like Irritable Bowel Syndrome (IBS)?
Is FODZYME® a cure for conditions like Irritable Bowel Syndrome (IBS)?
No. FODZYME® is a digestive enzyme supplement, not a cure for Irritable Bowel Syndrome (IBS) or any medical condition. It works by breaking down specific FODMAP carbohydrates in food during digestion, which may reduce symptoms triggered by those foods — including bloating, gas, and abdominal pain. FODZYME® does not address the underlying causes of IBS.
If you have been diagnosed with IBS or suspect you have a digestive disorder, consult a gastroenterologist or registered dietitian. FODZYME® can be used alongside medical treatment and the low-FODMAP diet as directed by your healthcare provider.
Why is FODZYME® a powder instead of a capsule?
Why is FODZYME® a powder instead of a capsule?
FODZYME®’s powdered format mixes directly with your food for instant action on FODMAPs—no waiting for a capsule to dissolve. This allows for:
- More immediate breakdown of problematic carbs.
- Flexible dosing based on your meal’s FODMAP content.
- Even distribution for better overall effectiveness in reducing digestive discomfort.
Is FODZYME® safe to take while I'm pregnant or breastfeeding?
Is FODZYME® safe to take while I'm pregnant or breastfeeding?
FODZYME®’s enzymes work on your food without entering your body, making it a low-risk option. However, because studies on pregnant or breastfeeding women are limited for ethical reasons, there’s no concrete evidence it’s unsafe—but it’s best to consult your physician before use.
Keep in mind that a low FODMAP diet isn’t generally advised during pregnancy due to potential nutritional restrictions, so always prioritize a nutrient-rich diet. Rest assured that all ingredients are GRAS-certified and undergo rigorous third-party testing for safety and quality.